When Tom's harassment gets out of hand, Jerry writes to his Cousin Muscles, a tough inner city mouse, and asks for his help.
Tom subjects Jerry to his usual harassment; but the cat finds a new enemy, and the mouse finds a new friend, in the canary of the house.
Mammy Two-Shoes threatens to throw Tom out of the house if he makes a mess. Jerry sees an opportunity to rid himself of his feline nemesis.
Tom's chasing Jerry when he runs right into a sleeping dog and the two of them must work together to fend him off.
Jerry's eccentric uncle, Pecos, a Texan mouse, comes to spend the night with him before his musical performance on television the next day. He decides to rehearse with his guitar for the performance but each time he plays, one of his guitar strings snaps off. Fortunately, he is able to replace them by plucking off one of Tom's whiskers each time. Tom is rather reluctant about this and tries to hide to protect his whiskers from Uncle Pecos.
It's a grand day at the beach for Tom and his girlfriend Tootles — that is, until Jerry shows up.
Mammy Two-Shoes tells Tom and Butch that the cat who gets rid of the icebox-raiding, breadbox-invading mouse (Jerry) is the one who can stay.
Tom filches a drumstick from a fresh-baked chicken. When Mammy is about to discover him, he hands it off to Jerry; this lets him be a hero to Mammy and still get his chicken. Jerry is miffed, and sees his chance to retaliate: Spike is very possessive of his bone. Jerry keeps stealing the bone and planting it on Tom. Finally, Jerry bores a hole in the bone, inserts a bolt, and gets Tom to swallow a magnet. The bone keeps coming back to Tom, even through a fence. Finally, as Tom runs off followed by Spike, Jerry, who's been hiding in a tin can, is also dragged along.
Mickey's trying to do some yardwork, but Pluto wants to play. They end up indoors; Mickey breaks a screen, spreads flypaper, and they both get stuck.
Spike has just washed his pup. Tom and Jerry's chase knocks him into a mud puddle. Spike makes Tom clean him up again and promise to keep him clean which of course is Jerry's opening to get Tom in trouble.
Tom is all set to eat Jerry when a hawk swoops down and grabs Jerry. To get Jerry back, Tom poses as a female hawk and quickly finds his new lover to be more than he bargained for.
Mammy Two-Shoes replaces Tom with a younger cat who is a lightning-quick mouser. Tom and Jerry form an alliance in order to get rid of this dangerous newcomer.
While streetworker Mickey romances Minnie, Mickey's nephews Morty and Ferdie take control of his steamroller and it's full speed ahead on a very destructive ride.
Donald takes a kayak trip. When he gets to his campsite, he unloads the kayak, fights with his folding chair, and goes to sleep. Meanwhile, the chipmunks of the forest (precursors of Chip 'n Dale), attracted by his squawking, make off with the huge pile of food he carelessly unloaded. They get the attention of a bear, who Donald is soon battling.
Donald's doing a little tree surgery when he spots Chip 'n' Dale gathering nuts. He saws off the branch outside their hole and paints it with tar, which Dale gets stuck in. Then Donald has a little fun with the long-handled pruning shears.
Tom, whose appetite was whetted by a radio cooking program, wants to make a meal out of the pet goldfish. Jerry, who is friends with the fish, does what he can to thwart their feline foe.
Tom has plans to take a nice long nap in a hammock, but Jerry has gotten there first and is snoozing happily, so the two fight it out to see who gets to sleep there.
Jasper is given an ultimatum by his master: break one more thing and you're out. Rodent Jerry does his best to make sure that his tormentor "gets the boot".
Donald Duck tries to exhibit his golfing ability to his nephews only to have them tease him with sneezes, noises and "trick" clubs. Finally, they put a grasshopper in a ball and it "jumps" all over.
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